Best Once Human settings for the NVIDIA RTX 5080 (2026)
On a NVIDIA RTX 5080 (paired with a balanced Intel Core i9-14900K-class CPU), Once Human runs at roughly 89 FPS at 4K with our optimized settings — up from about 90FPS with everything maxed. Here's the configuration and what each setting costs.
The NVIDIA RTX 5080 is a flagship 4K-class graphics card with 16GB of VRAM, and Once Human is a moderately demanding game. Paired with the Intel Core i9-14900K, it runs well at 4K — about 89 FPS with FrameCoach's optimized settings. That already clears a smooth frame rate on High, so our tuning keeps the visuals as high as possible instead of chasing extra frames.
Across resolutions you can expect around 262 FPS at 1080p and 157 FPS at 1440p, dropping to roughly 89 FPS at 4K. Its 16GB of VRAM is plenty for Once Human, so textures can stay maxed. The biggest free win is DLSS upscaling — set it to Quality for a large FPS boost at little visual cost.
| Resolution | All-High FPS | Optimized FPS |
|---|---|---|
| 1080p | 263 | 262 |
| 1440p | 159 | 157 |
| 4K | 90 | 89 |
⚡ Fine-tune this for your exact CPU & target FPS →
🎯 Can the NVIDIA RTX 5080 run Once Human? See the verdict →
What FPS does the NVIDIA RTX 5080 get in Once Human?
With FrameCoach's optimized balanced settings, the NVIDIA RTX 5080 averages around 89 FPS at 4K in Once Human — up from about 90 FPS with everything on High.
Can the NVIDIA RTX 5080 run Once Human at 1440p?
At 1440p with optimized settings, the NVIDIA RTX 5080 averages roughly 157 FPS in Once Human — a smooth experience.
What are the best Once Human settings for the NVIDIA RTX 5080?
Use a balanced preset, keep ray tracing off for maximum FPS, and ease the heaviest options like Shade and VFX down a notch. The full per-setting breakdown is above.
FPS figures are estimates from a generalized model (hardware tier × game load × per-setting weights), not live benchmarks — real performance varies by scene, drivers and game version.