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Best Devil May Cry 5 settings for the AMD R9 380 (4GB) (2026)

On a AMD R9 380 (4GB) (paired with a balanced Intel Core i5-8600K-class CPU), Devil May Cry 5 runs at roughly 64 FPS at 1080p with our optimized settings — up from about 42FPS with everything maxed. Here's the configuration and what each setting costs.

The AMD R9 380 (4GB) is a entry-level graphics card with 4GB of VRAM, and Devil May Cry 5 is a moderately demanding game. Paired with the Intel Core i5-8600K, it runs well at 1080p — about 64 FPS with FrameCoach's optimized settings, a clear jump from roughly 42 FPS with everything on High.

Across resolutions you can expect around 64 FPS at 1080p and 54 FPS at 1440p, dropping to roughly 31 FPS at 4K. Devil May Cry 5 offers ray tracing, but the AMD R9 380 (4GB) isn't built for it, so we leave it off. The biggest free win is FSR upscaling — set it to Quality for a large FPS boost at little visual cost.

ResolutionAll-High FPSOptimized FPS
1080p4264
1440p2554
4K1431
🚀 Biggest free win: enable FSR (Balanced) — about +55% FPS for a small sharpness trade.
Recommended settings
Upscaling — FSRBalanced+55% FPS
Devil May Cry 5 (RE Engine) supports FSR; DLSS via mods. A near-free FPS boost - and this fast action game wants high, steady frames.
Ray TracingOffsaves FPS
Ray-traced reflections in the Special Edition. A real cost - keep Off for the high frame rates stylish combat needs.
Texture QualityMax-1% FPS
Surface sharpness, shown with a VRAM estimate. On 8GB cards keep textures at High, not Max.
Shadow QualityHighbaseline
Shadow resolution and range. High is the value pick over Max.
Mesh QualityHighbaseline
Detail on characters and demons. High looks great; Medium for frames.
Effects QualityMediumbaseline
Combat sparks and devil-trigger effects. Medium keeps fast fights smooth and readable.
Volumetric LightingMediumbaseline
Atmospheric fog and light shafts. Medium is an easy, near-invisible win.
Ambient OcclusionSSAObaseline
Soft contact shadows for depth. SSAO is cheap and good-looking.
Anti-AliasingTAAbaseline
Edge smoothing. TAA is clean and cheap.

⚡ Fine-tune this for your exact CPU & target FPS →

🎯 Can the AMD R9 380 (4GB) run Devil May Cry 5? See the verdict →

Devil May Cry 5 on other GPUs
Other games on the AMD R9 380 (4GB)
Frequently asked

What FPS does the AMD R9 380 (4GB) get in Devil May Cry 5?

With FrameCoach's optimized balanced settings, the AMD R9 380 (4GB) averages around 64 FPS at 1080p in Devil May Cry 5 — up from about 42 FPS with everything on High.

Can the AMD R9 380 (4GB) run Devil May Cry 5 at 1440p?

At 1440p with optimized settings, the AMD R9 380 (4GB) averages roughly 54 FPS in Devil May Cry 5; turn on upscaling or aim for a locked 60 for the best feel.

What are the best Devil May Cry 5 settings for the AMD R9 380 (4GB)?

Turn on FSR (Balanced), keep ray tracing off for maximum FPS, and ease the heaviest options like Shadow Quality and Mesh Quality down a notch. The full per-setting breakdown is above.

FPS figures are estimates from a generalized model (hardware tier × game load × per-setting weights), not live benchmarks — real performance varies by scene, drivers and game version.