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Can the NVIDIA RTX 4090 run The Callisto Protocol? (2026)

Yes
~72 FPS at 4K with optimized settings

The NVIDIA RTX 4090 is a flagship 4K-class card with 24GB of VRAM, and The Callisto Protocol is a demanding, graphically heavy game. Paired with a balanced Intel Core i9-14900K-class CPU it averages about 72 FPS at 4K with FrameCoach's tuned settings — up from roughly 73 FPS with everything on High.

ResolutionAll-High FPSOptimized FPS
1080p195195
1440p128127
4K7372
💡 The Callisto Protocol: Prone to shader-compilation stutter - ray tracing makes it worse.

At 1080p expect around 195 FPS, at 1440p about 127 FPS, and at 4K roughly 72 FPS with optimized settings. Its 24GB of VRAM is plenty for The Callisto Protocol. The Callisto Protocol doesn't use upscaling, so the gains come from trimming the heaviest settings.

🎛 See the full best-settings guide for The Callisto Protocol on the NVIDIA RTX 4090

⚡ Check your exact CPU & target FPS in the optimizer →

Can other GPUs run The Callisto Protocol?
Can the NVIDIA RTX 4090 run other games?
Frequently asked

Can the NVIDIA RTX 4090 run The Callisto Protocol?

Yes. With FrameCoach's optimized balanced settings, the NVIDIA RTX 4090 averages about 72 FPS at 4K in The Callisto Protocol.

What FPS does the NVIDIA RTX 4090 get in The Callisto Protocol at 1080p?

Around 195 FPS at 1080p with optimized settings (up from about 195 FPS on all-High).

How do I make The Callisto Protocol run better on the NVIDIA RTX 4090?

keep ray tracing off, and lower the heaviest settings a notch. FrameCoach's full per-setting guide for this exact combo shows what each option costs.

FPS figures are estimates from a generalized model (hardware tier × game load × per-setting weights), not live benchmarks — real performance varies by scene, drivers and game version.