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Can the AMD RX 480 (8GB) run Once Human? (2026)

Yes
~67 FPS at 1080p with optimized settings

The AMD RX 480 (8GB) is a entry-level card with 8GB of VRAM, and Once Human is a moderately demanding game. Paired with a balanced Intel Core i5-8600K-class CPU it averages about 67 FPS at 1080p with FrameCoach's tuned settings — up from roughly 44 FPS with everything on High.

ResolutionAll-High FPSOptimized FPS
1080p4467
1440p2661
4K1535
🚀 Biggest free win: enable FSR (Balanced) — about +55% FPS for a small sharpness trade.

At 1080p expect around 67 FPS, at 1440p about 61 FPS, and at 4K roughly 35 FPS with optimized settings. The single biggest improvement is FSR upscaling — set it to Quality.

🎛 See the full best-settings guide for Once Human on the AMD RX 480 (8GB)

💰 Where to buy
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Buy the AMD RX 480 (8GB)
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NVIDIA RTX 5060
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Can other GPUs run Once Human?
Can the AMD RX 480 (8GB) run other games?
Frequently asked

Can the AMD RX 480 (8GB) run Once Human?

Yes. With FrameCoach's optimized balanced settings, the AMD RX 480 (8GB) averages about 67 FPS at 1080p in Once Human.

What FPS does the AMD RX 480 (8GB) get in Once Human at 1080p?

Around 67 FPS at 1080p with optimized settings (up from about 44 FPS on all-High).

How do I make Once Human run better on the AMD RX 480 (8GB)?

Turn on FSR (Balanced) for the biggest free boost, keep ray tracing off, and lower the heaviest settings a notch. FrameCoach's full per-setting guide for this exact combo shows what each option costs.

FPS figures are estimates from a generalized model (hardware tier × game load × per-setting weights), not live benchmarks — real performance varies by scene, drivers and game version.