Best The Callisto Protocol settings for the NVIDIA RTX 4080 (2026)
On a NVIDIA RTX 4080 (paired with a balanced Intel Core i9-14900K-class CPU), The Callisto Protocol runs at roughly 80 FPS at 4K with our optimized settings — up from about 60FPS with everything maxed. Here's the configuration and what each setting costs.
The NVIDIA RTX 4080 is a flagship 4K-class graphics card with 16GB of VRAM, and The Callisto Protocol is a demanding, graphically heavy game. Paired with the Intel Core i9-14900K, it runs well at 4K — about 80 FPS with FrameCoach's optimized settings, a clear jump from roughly 60 FPS with everything on High.
Across resolutions you can expect around 174 FPS at 1080p and 105 FPS at 1440p, dropping to roughly 80 FPS at 4K. The Callisto Protocol supports ray tracing and the NVIDIA RTX 4080 can technically run it, but it's the single most expensive option here — we keep it off to hit a smooth frame rate and suggest turning it on only if you have frames to spare. Its 16GB of VRAM is plenty for The Callisto Protocol, so textures can stay maxed. The biggest free win is DLSS upscaling — set it to Quality for a large FPS boost at little visual cost.
| Resolution | All-High FPS | Optimized FPS |
|---|---|---|
| 1080p | 176 | 174 |
| 1440p | 106 | 105 |
| 4K | 60 | 80 |
⚡ Fine-tune this for your exact CPU & target FPS →
🎯 Can the NVIDIA RTX 4080 run The Callisto Protocol? See the verdict →
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What FPS does the NVIDIA RTX 4080 get in The Callisto Protocol?
With FrameCoach's optimized balanced settings, the NVIDIA RTX 4080 averages around 80 FPS at 4K in The Callisto Protocol — up from about 60 FPS with everything on High.
Can the NVIDIA RTX 4080 run The Callisto Protocol at 1440p?
At 1440p with optimized settings, the NVIDIA RTX 4080 averages roughly 105 FPS in The Callisto Protocol — a smooth experience.
What are the best The Callisto Protocol settings for the NVIDIA RTX 4080?
Turn on DLSS (Quality), keep ray tracing off for maximum FPS, and ease the heaviest options like Shadow Quality and Screen Space Reflections down a notch. The full per-setting breakdown is above.
FPS figures are estimates from a generalized model (hardware tier × game load × per-setting weights), not live benchmarks — real performance varies by scene, drivers and game version.